Advin Nephrology

Dry Citrate Haemodialysis Concentrate<br />
“Auxin +” Dialysis Fluid (Dialysate) contains glucose, salts and various substances at the correct concentration for the body.<br />
“Auxin +” Dialysis Fluid (Dialysate) granulated form of Haemodialysis Concentrate (Dry Citrate Haemodialysis Concentrate).<br />
   The main function of the Dialysis Fluid, is to remove waste material from the blood and to keep useful material from leaving the blood. Electrolytes and water are some materials included in the dialysate so that their level in the blood can be controlled.<br />
 Auxin + Dialysis Fluid (Dialysate) consist of : <br />
PART A- Sodium Chloride, Potassium Chloride, Calcium Chloride, Magnesium Chloride, Sodium Acetate, and Citric Acid Anhydrous. <br />
PART B-  Sodium Chloride  and Sodium Bicarbonate.<br />
Dialysis Fluid (Dialysate) also known as Dry Citrate Haemodialysis Concentrate , Dialysis concentrates, Dialysis Solutions, Haemodialysis Concentrate, Dry Granulated Haemo Dialysis Concentrate, Haemodialysis dry powder, Haemodialysis Fluid.<br />
Composition of Dry Granulated Haemodialysis Concentrate:<br />
Each 100 Gms of dry concentrated Part –A Contains:<br />
Sodium Chloride (I.P.)87.01 g<br />
Potassium Chloride (I.P.) 3.17 g<br />
Calcium Chloride (I.P.)4.27 g<br />
Magnesium Chloride (I.P.)1.95 g<br />
Sodium Acetate (I.P.)0.53 g<br />
Citric Acid Anhydrous (I.P.)3.01 g<br />
 <br />
 <br />
Millimoles per liter after preparing PART–A solution & dilution with purified water & mixture with PART-B <br />
Sodium136.00<br />
Potassium2.20<br />
Calcium1.50<br />
Magnesium0.50<br />
Bicarbonate36.50<br />
Chloride103.00<br />
Acetate0.33<br />
Citrate0.81<br />
 <br />
Dilution Ratio:<br />
Part A SolutionPart B SolutionPurified Water<br />
1 Vol.1.83 Vol.34 Vol<br />
 <br />
Advantage of Dry Granulated Concentrate:


Less storage place required
Easy to transport & reduces operating cost
Prepared freshly before dialysis so no chance and time for bacterial growth
Long self life of the product
Provides proper correct concentration for the body

Advantage of Dry Citrate Haemodialysis Concentrate:


Reduces Heparin need in dialysis patients
Increases dialysis dose Kt/V (>1.2) and URR (>70%)
Improved acid-base status
Reduced inflammation
Reduces clotting in case of Heparin-free Hemodialysis
Can be used in Liver Failure patients undergoing Hemodialysis
Better Kt/V in case of Dialyzer Reuse due to better clearing of fibres
Number of Dialyzer Re-use increases significantly (60-100%)
Does not cause Thrombocytopenia
No Heparin Antibodies & Reduces cost of Heparin & Significant reduction in bleeding
No Heparin-related complications viz Osteoporosis, Pruritis, disturbed Lipid Metabolism
Significantly less or no clotting in patients with frequent dialyzer clotting
Elimination of Acetate-related complications
Improved tolerance to treatment