Description
Crolibulin, also known as EPC2407 and crinobulin, is a small molecule tubulin polymerization inhibitor with potential antineoplastic activity. Microtubulin inhibitor EPC2407 binds to the colchicine-binding site on beta-tubulin and inhibits the polymerization of tubulin into microtubules, which may result in cell cycle arrest, the induction of apoptosis, and the inhibition of tumor cell proliferation. As a vascular disruption agent (VDA), this agent also disrupts tumor neovascularization, which may result in a reduction in tumor blood flow and tumor hypoxia and ischemic necrosis.More information, please visit the website: http://www.bocsci.com/description.asp?cas=1000852-17-4
- Inhibitor
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More about
Boc Sciences
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Year
Established
Business type
- Industry / Manufacturer
Keywords
- BOC Sciences
Contact and location
- Linna Green
- +1 631 xxxxxxxx
- New York / | United States